Each tablet contains: Cowslip flower extract 5 mg • Scotch Thistle flower extract 5 mg • Henbane herb extract 0.2 mg. Other Ingredients: Lactose, Aqua, Wheat Starch, Calcium Behenate.
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Below is general information about the effectiveness of the known ingredients contained in the product Cordiodoron Tablets. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of henbane.
There is insufficient reliable information available about the effectiveness of Scotch thistle.
Below is general information about the safety of the known ingredients contained in the product Cordiodoron Tablets. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when used orally. Cowslip has been used with apparent safety in combination with other herbs (SinuComp, Sinupret, Sinupret +, Bronchipret) (374,379,13557).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
POSSIBLY SAFE ...when henbane leaf is used orally and appropriately, short-term. Henbane leaf powder has been used with apparent safety in single doses of up to 1 gram, which have been standardized to contain 500-700 mg of total alkaloids. The maximum daily dosage should not exceed 3 grams, corresponding to 1500-2100 mg of total alkaloids (2,18).
LIKELY UNSAFE ...when the leaf is used orally in doses above 3 grams daily. This maximum tolerated dose contains 1500-2100 mg of total alkaloids, which include hyoscyamine and scopolamine. These alkaloids have a narrow therapeutic range; excessive doses can cause poisoning and death (2,18). There is insufficient reliable information available about the safety of henbane seed and flower.
PREGNANCY AND LACTATION: LIKELY UNSAFE
when used orally because of its risk of poisoning (18).
There is insufficient reliable information available about the safety of Scotch thistle.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Cordiodoron Tablets. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Concomitant use of henbane can have additive anticholinergic effects and adverse effects with amantadine, antihistamines, atropine, belladonna alkaloids, hyoscyamine, phenothiazines, procainamide, scopolamine, and tricyclic antidepressants (2).
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Below is general information about the adverse effects of the known ingredients contained in the product Cordiodoron Tablets. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, cowslip in combination with other herbs is generally well tolerated (95907). Studies show it can cause gastrointestinal adverse effects and allergic skin reactions (374,379,13557).
Dermatologic ...Orally, cowslip in combination with other herbs can cause allergic skin reactions (374,379,13557).
Gastrointestinal ...Orally, cowslip in combination with other herbs can cause gastrointestinal adverse effects (374,379,13557).
General ...Orally, henbane can cause anticholinergic effects including dry mouth, vision disturbances, tachycardia, difficult urination, constipation, and skin flushing (2,18). At higher doses, poisoning can occur due to the hyoscyamine and scopolamine constituents of henbane. Symptoms of toxicity include hyperpyrexia and somnolence, followed by CNS stimulation with restlessness, hallucinations, delirium, memory impairment, ataxia, and manic episodes, followed by exhaustion and coma. Henbane can cause death by asphyxiation (2,18,100917).
Cardiovascular ...Orally, henbane can cause tachycardia, especially at higher doses (2,18,100917).
Dermatologic ...Orally, henbane reduces sweating, resulting in flushing of the skin and hyperpyrexia (2,18,100917).
Gastrointestinal ...Orally, henbane causes reduced muscle activity in the bowel, leading to constipation (2,18,100917).
Genitourinary ...Orally, henbane can cause difficulty with urination (2,18,100917).
Neurologic/CNS ...Orally, high doses of henbane can cause toxicity due to its hyoscyamine and scopolamine constituents. Neurologic symptoms of henbane toxicity include somnolence, followed by CNS excitation involving restlessness, hallucinations, memory impairment, delirium, and manic episodes, followed by exhaustion and coma (2,18,100917).
Ocular/Otic ...Orally, high doses of henbane can cause toxicity due to its hyoscyamine and scopolamine constituents. Ocular symptoms of henbane toxicity include visual disturbances (2,18,100917).
Other ...Orally, high doses of henbane can cause toxicity due to its hyoscyamine and scopolamine constituents. Toxicity can result in coma and death by asphyxiation in some cases (2,18,100917). Treatment of henbane toxicity includes stomach lavage, activated charcoal, supportive therapy, and, in severe cases, the antidote physostigmine (100917).
General ...No adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted.