Each capsule contains: 4-Androstene 3, 17-dione 50 mg.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
This product has been discontinued by the manufacturer. This product contains the ingredient androstenedione. In March 2004, the U.S. Food and Drug Administration told manufacturers of products containing this ingredient to immediately stop distribution. The FDA considers these dietary supplements to be adulterated drugs due the lack of historical data regarding dietary use that establishes a reasonable expectation of safety. There are concerns that these products are unsafe. Androstenedione might have potent androgenic effects and lead to serious side effects including impotence, liver problems, and increased cancer risk (12001). In January 2005 legislation went into effect in the United States called the Anabolic Steroid Control Act of 2004. This reclassifies androstenedione from a dietary supplement to an anabolic steroid, which is a schedule III controlled substance (8639).
Below is general information about the effectiveness of the known ingredients contained in the product Androstene Power. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Androstene Power. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY UNSAFE ...when used orally. Androstenedione has been associated with significant side effects, including increased risk of breast, pancreatic, and prostate cancer (672,3861,6000). In addition, there are safety concerns that the potency and purity of androstenedione products can differ significantly from the product labeling (10641).
CHILDREN: LIKELY UNSAFE
when used orally.
Androstenedione could potentially cause premature closure of the bone growth plates and precocious puberty (674,111132).
PREGNANCY: LIKELY UNSAFE
when used orally.
Androstenedione might induce labor (673).
LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Androstene Power. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, androstenedione might increase the effects and adverse effects of estrogens.
 Details
Androstenedione is a precursor to estrogen and seems to increase estrogen levels (1905,3861,6000,7236,8138,19563,97845,111132,111134). However, androstenedione is converted to estrogen only in low estrogen environments. Patients taking estrogen do not have low estrogen levels because of the estrogen treatment. Therefore, androstenedione is unlikely to be converted to estrogen in these patients. However, until more is known, use with caution or avoid using.
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Below is general information about the adverse effects of the known ingredients contained in the product Androstene Power. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, androstenedione may be unsafe.
Serious Adverse Effects (Rare):
Orally: hepatotoxicity; breast and endometrial cancer (females); pancreatic and prostate cancer (males); and adverse genitourinary effects.
Cardiovascular ...Orally, there is some concern that androstenedione might increase risk of heart disease in men. Androstenedione decreases high-density lipoprotein (HDL) cholesterol (1905,6000,7236,31279,111134).
Dermatologic ...Orally, androstenedione might cause acne in men by decreasing endogenous testosterone production and increasing estrogen. In women, androstenedione might cause male-pattern baldness, hair growth, acne, and coarsening of the skin (674,111132).
Endocrine ...Orally, androstenedione might decrease endogenous testosterone production and increase estrogen in men (1905,3861,6000,7236,8138,97845). Changes in testosterone levels are variable and might depend on length of supplementation and age (1905,3861,6000,7236,8138,31250,97845,111132). In women, androstenedione can increase testosterone levels (19563,19564,111132). Theoretically, these changes can affect behavior and physical characteristics.
Genitourinary ...Orally, androstenedione possibly alters levels of estrogen and testosterone in men (1905,3861,6000,7236,8138,97845,111132,111134). Theoretically, this might cause decreased spermatogenesis, gynecomastia, testicular atrophy, and prostate hypertrophy (6000,31266,111132). There is one case report of two episodes of priapism associated with androstenedione use in a 30-year-old man (5089). Also, there is one case report of severe oligospermia, reduced libido, impotence, and testicular atrophy in a 29-year-old male recreational bodybuilder using androstenedione (97844). In women, androstenedione may theoretically cause clitoral hypertrophy and menorrhea (674,31266,31280,111132).
Hepatic ...Orally, androstenedione might cause hepatotoxicity. Testosterone derivatives similar to androstenedione have been associated with hepatic toxicity (3861). Consider monitoring liver function tests (LFTs) in patients using androstenedione.
Oncologic ...Orally, androstenedione might potentially increase the risk of pancreatic and prostate cancer in men (672,6000). There is preliminary evidence that androstenedione might stimulate prostate cancer cell growth (672,8138,31280,31283). However, population research shows that higher blood levels of androstenedione is not associated with an increased risk of prostate cancer in mean with enlarged prostates (97841). Some androstenedione products are combined with other supplements such as dehydroepiandrosterone, puncture vine, saw palmetto, indole-3-carbinol, and chrysin (DION) to lessen the effects of androstenedione on increased levels of estradiol and DHT. However, this combination does not seem to help (8138). In women, androstenedione can increase testosterone levels. Theoretically, this might increase the risk of breast and endometrial cancer (31273).
Psychiatric ...There is some concern that androstenedione might cause or worsen depression in women. Some women with severe major depression seem to have increased endogenous androstenedione concentrations; however, it is not known if supplements can actually cause this adverse effect (6796).
