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Neutropenia

Synonyms

  • AIN, autoimmune disease, blood disease, blood disorder, chemotherapy, congenital, congenital neutropenia, cyclic, cyclic neutropenia, immune disorder, febrile neutropenia, granulocytes, hematological autoimmune disorder, hematological disorder, immune system disorder, Kostmann disease, Kostmann's syndrome, low neutrophils, neutropaenic, neutropaenia, neutropenic, neutrophil granulocytes, neutrophils, primary autoimmune neutropenia, primary immune neutropenia, SCN, secondary autoimmune neutropenia, severe congenital neutropenia, white blood cells.

Background

  • Neutropenia is defined as a low number of neutrophil granulocytes, a type of white blood cell, in the body. White blood cells serve as the body's primary defense mechanism against infection and disease. In a healthy body, neutrophils make up 50-60% of circulating white blood cells. Neutropenic patients have an absolute neutrophil count (ANC) that is lower than 1,500 cells per microliter of blood.
  • Therefore, patients with neutropenia are more susceptible to disease and infection. Severe cases of neutropenia may even become life threatening.
  • Mild neutropenia usually causes no symptoms. Severe neutropenia increases the risk of infection, especially in the lungs, kidneys, blood, and/or skin.
  • Neutropenia can be acute (lasting less than three months) or chronic (lasting longer than three months). The condition occurs when the bone marrow does not produce enough neutrophils or an increased number of neutrophils are destroyed in the body. For instance, neutropenia is a common side effect of chemotherapy.
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Classification

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Types

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Causes

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Symptoms

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Diagnosis

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Treatment

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Integrative Therapies

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Prevention

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Author Information

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Bibliography

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.