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Caprylic acid

Synonyms/Common Names/Related Substances:

  • [1(-14)C]octanoate, 13C-octanoic acid, DL-1,2-dioctanoylglycerol, 1,2-DiC8, 1,3-DiC8 , alpha-hydroxy caprylic acid, medium-chain fatty acid, medium chain triglyceride (MCT), monocaprylin, octanoic acid, suberic acid.
  • Combination product examples: Caprinol® (caprylic sodium caprylate, pau d'arco concentrate, and vitamin A), Capryl® (caprylic acid (from calcium, magnesium, and zinc caprylates)), Oxepa® (gamma-linolenic acid, caprylic acid, eicosapentaenoic acid, taurine, vitamin A, vitamin E, and vitamin C).

Clinical Bottom Line/Effectiveness

Brief Background:

  • Caprylic acid is an eight-carbon fatty acid naturally found in palm and coconut oil, and in the milk of humans and bovines. Caprylic acid is classified as a medium-chain fatty acid and chemically known as octanoic acid. The United States Food and Drug Administration (FDA) has approved caprylic acid as generally recognizable as safe (GRAS) status (1). It is used as parenteral nutrition in patients who require nutrition supplementation, as well as in some drugs, foods, and cosmetics (2). Labeled caprylic acid can be used as a method of assessing gastric emptying.
  • There is insufficient clinical data available to support the used of caprylic acid for claimed therapeutic uses.

Dosing/Toxicology

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Precautions/Contraindications

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Mechanism of Action

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History

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Evidence Table

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Evidence Discussion

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Products Studied

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.