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Coagulation disorders

Related Terms

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Background

  • Coagulation disorders occur when the blood does not form clots properly. Blood clots are clumps of different types of blood cells and clotting factors that stop bleeding after an injury. Patients with coagulation disorders may develop too many blood clots that eventually block blood vessels, while others may not clot enough and have excessive bleeding in the body. Both of these conditions range from mild to severe and life threatening.
  • The process of blood clotting is called coagulation or hemostasis. There are three major phases of coagulation: narrowing of blood vessels, activation of platelets, and activation of blood clotting factors.
  • Phase 1: When a blood vessel (vein or artery) becomes injured, it narrows to slow blood flow so that clotting can begin. At the same time, the blood that has leaked outside of the injured blood vessel presses against the vessel to help prevent further blood loss.
  • Phase 2: Blood cells called platelets are activated to move towards the site of injury. The platelets produce a substance called von Willebrand factor, which has a major role in blood coagulation and helps platelets stick to the blood vessel's walls.
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Causes

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Signs and Symptoms

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Diagnosis

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Treatment

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Integrative Therapies

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Prevention

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.