Related Terms

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Background

• Scleroderma is a group of disorders that cause the skin and the fibers that provide support and framework for the body (called connective tissues) to harden and tighten. It typically starts with a few dry patches of skin on the face and hands. Over time, these patches of skin become thicker and harder, and more and more skin becomes affected. In some cases, the condition may also involve the internal organs and blood vessels.
• Scleroderma is classified into two major categories: localized scleroderma and systemic scleroderma. Localized scleroderma only affects the skin. Often, localized conditions improve or go away on their own over time. However, the skin changes and damage that occurred when the disease was active are permanent.
• Systemic scleroderma is a more serious type of scleroderma that affects the skin, deep tissues below the skin, blood vessels, and internal organs. When the internal organs become hard, they no longer function properly and death may occur. Systemic scleroderma may develop suddenly or it may start with the skin and progress gradually to the internal organs.
• Scleroderma is a type of autoimmune disorder because it occurs when a patient's immune system does not function properly. Normally, the immune system helps fight against diseases and infections. In scleroderma patients, the immune system attacks the person's own cells. However, researchers have not discovered what causes this abnormal immune response.
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Causes

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Signs and Symptoms

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Complications

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Diagnosis

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Treatment

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Integrative Therapies

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Prevention

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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