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DMSO (dimethyl sulfoxide)

Synonyms/Common Names/Related Substances:

  • C2H6OS, dimethyl sulphoxide, dimethylis sulfoxidum, methyl sulfoxide methyl sulphoxide, NSC-763, SQ-9453, Rimso-50®, sulphinybismethane.

Clinical Bottom Line/Effectiveness

Brief Background:

  • Dimethyl sulfoxide (C2H6OS), or DMSO, is a sulfur-containing organic compound. It occurs naturally in vegetables, fruits, grains, and animal products. DMSO is formed as a by-product of paper manufacturing and is used as an industrial solvent.
  • DMSO is available for both nonmedicinal and medicinal uses. The major clinical use of DMSO is to relieve symptoms of interstitial cystitis. However, information from systematic reviews also suggests the potential for benefit for complex regional pain syndrome (1;2;3). Strong evidence for other uses is lacking.
  • Due to the potential toxic and adverse effects associated with DMSO, use should be under the advisement of a healthcare practitioner.

Dosing/Toxicology

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Precautions/Contraindications

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Mechanism of Action

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History

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Evidence Table

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Evidence Discussion

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Products Studied

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.