Related Terms

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Background

• Daio-kanzo-to is a Kampo formula that includes a mixture of rhubarb and licorice. Traditionalists consider it a safe remedy for habitual constipation and other abdominal symptoms.
• One ingredient, rhubarb, contains known laxative constituents (anthraquinones) similar to those found in approved over-the-counter laxative preparations. The other ingredient, licorice, reduces side effects by protecting mucous membranes. However, there is no meaningful evidence for any such protective effect, nor indication that such a protective effect is needed. Furthermore, licorice presents significant safety risks.
• The dosage used in clinical trials ranges from 0.5 to 1.5g per day. Adjustments to the dose may be necessary according to the needs of the individual patient.

Theory/Evidence

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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