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Differential display (DD) analysis

Related Terms

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Background

  • General: Genes (deoxyribonucleic acid or DNA) are considered the building blocks of life because they provide instructions for all the cells in the body. Genes, which are located inside cells (in the nucleus specifically), control an organism's development and functions by instructing cells to make new molecules, usually proteins. Proteins are organic compounds made of amino acids and the sequence of the amino acids in a protein is defined by a gene. Proteins are required for the growth and maintenance of the body.
  • DNA is a long, thread-like (double-helix) molecule made up of large numbers of nucleotides. Nucleotides are the building blocks of DNA and are made of nitrogen bases, sugars, and phosphate. Nitrogen bases are of two types: purines, such as adenine (A) and guanine (G), and pyrimidines, such as cytosine (C) and thymine (T). Long strands of nucleotides form nucleic acids.
  • Ribonucleic acid (RNA) is a nucleic acid that helps in protein synthesis, which is important for growth and maintenance of the body. RNA is formed under the direction of DNA and both help to form amino acids, which are the building blocks of protein.
  • Differential display: The differential display (DD) technique was developed 13 years ago as a systematic method for studying eukaryotic gene expression. Eukaryotic cells are complex organized structures that are contained within a membrane. Gene expression is the conversion of the information contained in a gene first into messenger RNA and then to a protein. Messenger RNA (mRNA) is a ribonucleic acid molecule that directs protein production. The detection of any variation in the gene expression helps in determining any changes in the body, which may further develop into diseases. Hence, this technique helps in the early detection of diseases.
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Methods

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Research

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Implications

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Limitations

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Safety

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Future Research

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.