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Ignatia (Strychnos ignatii)

Synonyms/Common Names/Related Substances:

  • Ignatia, Ignatia amara, Ignatius bean, Lu Song Guo, St. Ignatius bean, Strychnos ignatia.
  • Combination formulations: Mastrodynon.

Clinical Bottom Line/Effectiveness

Brief Background:

  • Ignatia amara is a homeopathic remedy derived from the seeds of the St. Ignatius bean, Strychnos ignatii, a tree found in the Philippines and other parts of Southeast Asia. It is used as a homeopathic remedy because of its effects on the nervous system.
  • Commonly called "homeopathic Prozac," Ignatia is often used in treating grief stages. Ignatia was commonly used in the 1800s but has not been studied in modern scientific trials. Although there is little scientific evidence regarding the medicinal use of ignatia, it was added to Materia Medica in the early 1800s.
  • One study verified the effectiveness of the use of homeopathic remedies containing ignatia amara complexes as an alternative to placebo. The ignatia treatment was well tolerated with a low risk of side effects (1).
  • Although ignatia contains the highly poisonous strychnine, homeopathic remedies containing the extract are diluted enough to be considered safe for use. Ignatia's effectiveness may be compromised by concurrent use with homeopathic Coffea, Nux vomica or Tabacum.

Dosing/Toxicology

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Precautions/Contraindications

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Mechanism of Action

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History

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Evidence Table

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Evidence Discussion

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Products Studied

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.