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Jequirity (Abrus precatorius)

Synonyms/Common Names/Related Substances:

  • 2,3,6-Tri-O-methyl-D-glucose, 2,3,6-tri-O-methyl-D-mannose, 3-O-[6'-methyl-beta-D-glucuronopyranosyl]-3beta,22beta-dihydroxyolean-12-en-29-oic acid methyl ester, 3-O-beta-D-glucuronopyranosylsophoradiol methyl ester, (20S,22S)-3beta,22-dihydroxycucurbita-5(10),24-diene-26,29-dioic acid delta-lactone, abrin, abrin-I, abrin-II, abrin-III, abrin A, abrin B, abrin C, abrine, abruoside A, abruoside B, abruoside C, abruoside D, abruquinone A, abruquinone B, abruquinone D, abruquinone E, abruquinone F, abruquinone G, Abrusabrus (L.) W.Wight, Abrus agglutinin, Abrus cantoniensis, Abrus precatorius Linn., Abrus pulchellus, abrus seed, abrus-a, abrusgenic acid, abruslactone, abrusogenin, aivoeiro, AP-3, APA-1, APA-II, arraccu-mitim, Ayurvedic phytomedicine, bead vine, beta-cholanic acid, black-eyed Susan, blackeyed Susan, Buddhist rosary bead, cain ghe, Carolina muida, chapelet (French), colorine, coral bean, crab's eye, crabs eye, deadly crab's eye, degraded glucomannan, ellagic acid, essential amino acids, flavonol glycoside 7,3',5'-trimethoxy-4'-hydroxy flavone-3-O-beta-D-galactosyl-(l --> 4)-alpha-L-xyloside, gallic acid, Glycine abrus L., graines reglisse (French), gunchi (Hindi), gunja (Bengali, Gujarati, Hindi, Marathi, Oriya, Telugu), hint meyankoku, hung tou (Chinese), hyaphorine, Indian bead, Indian licorice, Indian liquorice, isotoxic proteins, jequerit, jequirity bean, jequirity seed, jumble beads, juquiriti, lady bug bean, lady bug seed, lectins, legume, Leguminosae (family), liane reglisse (French), lipids, love bean, lucky bean, ma liao tou, methyl abrusgenate, ojo de pájaro, paratella, paternoster, peonia, peonia de St. Tomas, peronilla, phytoagglutinin, phytotoxin, pois rouge (French), prayer beads, prayer head, precatorine, precatory bean, rakat, ratti (Gujarati, Hindi), reglisse (French), rosary beads, rosary pea, rosary peas, ruti, rutti, seminole bead, sophoradiol, tentos da America (Portuguese), temtos dos mundos (Portuguese), tento muido (Portuguese), to-azuki (Japanese), tribal pulse, triterpenoid saponin-1, triterpenoid saponin-2, weather plant, weesboontje (Dutch), wild licorice.
  • Note: Ingestion of Abrus precatorius seeds has many toxic side effects, possibly resulting in severe gastrointestinal symptoms and even death.

Clinical Bottom Line/Effectiveness

Brief Background:

  • The seeds of Abrus precatorius exist in a variety of colors, such as black, orange, and, most commonly, glossy red (1). Although Abrus precatorius seeds have been traditionally used to stimulate labor and as an abortifacient, oral use is not recommended. Abrin, a constituent of Abrus precatorius, is toxic at 5mg, and ingestion of one bean by a child may be fatal (2). The common name for Abrus precatorius is precatory bean.
  • Abrin, a constituent of Abrus precatorius, is being investigated for the treatment of experimental cancers and is used as a "molecular probe" to investigate cell function (3).
  • A lectin from Abrus precatorius has been used glycohistochemically to identify the microglial cell (MGC) activation in autoptic brain samples from Alzheimer's disease (AD) subjects (4).
  • Ingestion of Abrus precatorius seeds has many toxic side effects, possibly resulting in severe gastrointestinal symptoms and even death.

Dosing/Toxicology

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Precautions/Contraindications

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Mechanism of Action

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History

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Evidence Table

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Evidence Discussion

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Products Studied

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.