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Adrenal extract
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy.

Related Terms

  • ACE, Adrena Support©, adrenal, adrenal complex, adrenal concentrate, adrenal cortex extract, adrenal factors, adrenal substance, glandular, protomorphogen (adrenal), suprarenal extract, whole adrenal extract.

Background

  • Adrenal extracts are derived from the adrenal glands of cows, pigs, or sheep gathered from slaughterhouses. The adrenal glands, which are above the kidneys, secrete adrenal hormones. The adrenal medulla secretes epinephrine (adrenaline) and norepinephrine (noradrenaline) while the adrenal cortex secretes a group of hormones called corticosteroids.
  • Adrenal extracts have been used medicinally since 1931, primarily in the injectable form. Today, adrenal extract is available only in the form of capsules or tablets. Commercially available adrenal extracts are made from the whole gland (whole or total adrenal extracts) or just from the outer part of the gland (adrenal cortex extracts). Although adrenal extract has been used to treat fatigue and low adrenal function, currently no human trials of adrenal extract have been performed to support these claims.

Evidence

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Dosing

The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.

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Safety

The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.