Siberian ginseng (Eleutherococcus senticosus)
Natural Standard Bottom Line Monograph, Copyright © 2012 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.
While some complementary and alternative techniques have been studied
scientifically, high-quality data regarding safety, effectiveness, and
mechanism of action are limited or controversial for most therapies.
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costs), and alternatives should be carefully considered. The below
monograph is designed to provide historical background and an overview of
clinically-oriented research, and neither advocates for or against the use
of a particular therapy.
Related Terms
- 1',5'-O-dicaffeoylquinic acid, 2,6-dimethoxy-4-[(1E)-3,3-dimethoxy-1-propenyl]phenyl beta-D-glucopyranoside, 2,6-dimethoxy-4-(3-hydroxy-propen-1-yl) phenyl-4-O-alpha-L-rhamno-pyranosyl-(1->6)-beta-D-glucopyranoside, 3-(4-O-beta-D-glucopyranosylferuloyl)quinic acid, 3,4-seco-lupane-20(29)-ene-3,28-dioic acid, 3',5'-O-dicaffeoylquinic acid, 4',5'-O-dicaffeoylquinic acid, 5'-O-caffeoylquinic acid and isomers, (7R,8S)-dihydrodehydrodiconiferyl alcohol 4,9'-di-O-beta-D-glucopyranoside, Acanthopanax senticosus, acanthopanaxoside E (3-O-beta-D-glucuronopyranosyl echinocystic acid 28-O-beta-D-glucopyranoside), acanthosides, ADAPT-232, aglycone, alimoxide, alpha-bisabolol, alpha-longipinene, arabinose, Araliaceae (family), Argoeleuter tablets, benzyl-O-alpha-L-rhamno-pyranosyl (1->6)-beta-D-glucopyranoside, beta-sitosterol, caffeic acid, carbohydrate, chlorogenic acid, Circu-ForteTM, Circulat®, ci wu jia (Chinese), ci wu ju (Chinese), ciwujia (Chinese), ciwujianoside B(1), ciwujianoside C(1), ciwujianoside C(2), ciwujianoside C(3), ciwujianoside C(4), ciwujianoside D(1), ciwujianoside D(2), ciwujianosides, ciwujiatone, complex polysaccharides, copteroside B, devil's bush, devil's shrub, dihydrodehydrodiconiferyl alcohol monopyranose, (E)-anethole, Eleu-kokk®, eleuterozid B, eleuterozid C, eleuterozid D, eleuthera, eleutheran, eleutheran A, eleutheran B, eleutheran C, eleutheran D, eleutheran E, eleutheran F, eleutheran G, eleuthero, eleuthero ginseng, eleutherococc, Eleutherococci radix, Eleutherococcus, eleutheroside B, eleutheroside B1, eleutheroside E, eleutheroside E(1), eleutheroside E(2), eleutherosides, episyringaresinol 4"-O-beta-D-glucopyranoside, erythro-1,2-bis(4-hydroxy-3-methoxyphenyl)-1,3-propanediol, erythro-1-(4-hydroxy-3-methoxy-phenyl)-2-{4-[(E)-3-hydroxy-1-propenyl]-2-methoxy-phenoxy}-1,3-propanediol, essential oil, extractum eleutherococci fluidum, ezoukogi (Japanese), ferulic acid, flavonoids, free phenolic acids, galactose, ginseng, ginsenosides, glucopyranosides, glucose, glucuronic acid, glycans, glycosides, guaia-6,9-dien-4beta-ol, gypsogenin 3-O-beta-D-glucuronopyranoside, Hedera senticosa, hederagenin 3-O-beta-D-glucuronopyranoside 6'-O-methyl ester, hyperin, hyperoside, Hyul-Tong-Ryung, Immuplant tablets, iridoid glycosides, isofraxidin, isofraxidin chiisanoside, isomaltol 3-O-alpha-D-glucopyranoside, Kan Jang®, Kan-Yang, lignans, lycoperodine-l, lyoniresinol, mannose, manyprickle acanthopanax, minerals, monoterpenoids, nicotinamide, oplopanone B, p-coumaric, phenolic acids, p-hydroxybenzoic, phytoestrogen, phytosterols, polyphenols, prickly eleutherococc, protein, protocatechuic acid, rel-5-(1R,5S-dimethyl-3R,4R,8S-trihydroxy-7-oxa-6-oxobicyclo[3,2,1]oct-8-yl)-3-methyl-2Z,4E-pentadienoic acid, rhamnose, rosmarinic acid, Russian root, rutoside, salvadoraside, schisandrin B, senticoside, sesamin, sesquiterpenoids, shigoka, Siberian ginseng wuchaseng extract, silphioside F, spiny eleutherococcus, stigmasterol, sucrose, syringaresinol, diglucoside, syringaresinol-di-O-beta-D-glucoside, syringic acid, syringin, tachioside, Taiga Wurzel, thorny bearer of free berries, thorny pepperbrush, thymidine, thymol, tortoside A, touch me not, triterpene saponins, triterpenoid saponins, untouchable, uronic acid, ussuri, ussurian, vanillic, vitamins, wild pepper, wu jia pi, wuchaseng, wu-jia, wujiaseng, xylose.
- Select combination products: ADAPT-232 (containing Rhodiola rosea, Schisandra chinensis, and Siberian ginseng), AdMax® (dried ethanol-water extracts from roots of Leuzea carthamoides, Rhodiola rosea, Eleutherococcus senticosus, and fruits of Schisandra chinensis), Aidi Injection (cantharis, Astragalus membranaceus, Acanthopanax senticosus root, Panax ginseng), Chisan® (extracts of Rhodiola rosea L., Schisandra chinensis Turcz. Baill., and Eleutherococcus senticosus Maxim.), Circulat® (also called Circu-ForteTM) (Siberian ginseng root, Rhaponticum carthamoides root, Panax ginseng root, Panax quinquefolius root, Pfaffia paniculata root, Rhodiola rosea root, Echinacea angustifolia root, Echinacea purpurea root, Ganoderma lucidum, Grifola frondosa, Hydrastis canadensis, Petiveria alliacea, Sutherlandia frutescens, Tabebuia avellanedae bark, Uncaria tomentosa root, Angelica sinensis root, Crataegus oxycantha fruit, Croton lechleri bark resin, Gingko biloba leaf, Hydrocotyle asiatica, Ruscus aculeatus root, Vaccinium myrtillus fruit), HT008-1 (composed of Panax ginseng, Siberian ginseng, Angelica sinensis, and Scutellaria baicalensis), Hyul-Tong-Ryung (Salvia miltiorrhiza, chrysanthemum, Acanthopanax senticosus, Cinnamomi ramulus, Eucommiae cortex, licorice, Puerariae radix, Crataegi fructus, Cassiae semen, safflower, peony root, dong quai), ImmunoGuard® (Andrographis paniculata Nees, Eleutherococcus senticosus Maxim., Schizandra chinensis Baill., and Glycyrrhiza glabra L. extracts), Kan Jang® (Echinacea purpurea, Adhatoda vasica, and Eleutherococcus senticosus), Kan-Yang (Andrographis and Siberian ginseng).
Background
- Siberian ginseng (Eleutherococcus senticosus, also known as Acanthopanax senticosus) is a small, woody shrub native to southeastern Russia, northern China, Korea, and Japan. Although Eleutherococcus senticosus is not related to true ginseng (Panax ginseng), the name Siberian ginseng became popular because the two plants shared some similar properties.
- Use of Siberian ginseng may date back over 2,000 years in China. Traditionally, Siberian ginseng has been used as an adaptogen, a compound that increases one's ability to adapt to environmental factors, including physical and emotional stress. Overall, there is currently little clinical evidence on the use of Siberian ginseng for this purpose or to treat any medical condition in humans.
- Siberian ginseng is called ci wu ju in traditional Chinese medicine (TCM). In TCM, Siberian ginseng is used to invigorate qi; strengthen the spleen; nourish the kidney; provide energy and vitality; and treat high blood pressure, inflammation, respiratory tract infections, ischemic heart disease, spasms, and hepatitis. In traditional Russian medicine, Siberian ginseng is used to stimulate the immune system. Shigoka, the Siberian ginseng rhizome, is a traditional medicine used as a tonic in northeastern Asia and far eastern Russia. It has also been used in traditional Korean medicine as a tonic and adaptogen to strengthen qi. Siberian ginseng is among the five adaptogens most commonly used by Western herbalists.
- Siberian ginseng has been added to yogurt products. Eleutherosides, active components of Siberian ginseng, have withstood pasteurization. Siberian ginseng is also called "eleuthero" in some products.
Evidence
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Dosing
The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
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Safety
The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.
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Interactions
Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.
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Author Information
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References
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
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Copyright © 2012 Natural Standard. Commercial distribution or
reproduction prohibited.
The information in this monograph is intended for informational purposes
only, and is meant to help users better understand health concerns.
Information is based on review of scientific research data, historical
practice patterns, and clinical experience. This information should not be
interpreted as specific medical advice. Users should consult with a
qualified healthcare provider for specific questions regarding therapies,
diagnosis and/or health conditions, prior to making therapeutic decisions.