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Yew (Taxus baccata, Taxus brevifolia, Taxus cuspidata, Taxus canadensis)
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy.

Related Terms

  • Chinwood, common yew, Coniferae (family), docetaxel, Eibe (Geman), euar (Manx), European yew, hagina (Basque), idegran (Swedish), if (French), Himalayan yew, Irish yew, iubhar (Scottish Gaelic), iúr (Irish), ivenenn (Breton), marjakuusi (Finnish), Japanese yew, NPacific yew, paclitaxel, phloroglucindimethylether (3,5-dimethoxyphenol), porsukagaci (Turkish), snottle berries, snotty grogs, T. bourcieri Carrière, taks (Danish), tasso (Italian), Taxaceae (family), taxine, taxis (Dutch), Taxol®, Taxomyces andreanae, Taxotere®, Taxus baccata L., Taxus brevifolia, Taxus canadensis, Taxus cuspidata, Taxus wallichiana, Taxuspine C., tejo (Spanish), tisa (Romanian), tis (Czech), western yew, ywen (Welsh), ywenn (Cornish).

Background

  • There are several kinds of yew including the English or European yew (Taxus baccata), Pacific yew (Taxus brevifolia) and Japanese yew (Taxus cuspidata). All species are considered poisonous; however, there is some debate about the medicinal value of the fruits (arils). The name 'taxus' may be related to the Greek 'toxon' (bow) and 'toxicon' (the poison with which the arrowheads were dressed).
  • Traditionally, the fruit of yew has been used as an antitussive (preventing or relieving cough), menstrual stimulant, abortifacient (induces abortion), diuretic and laxative. It is reported that the Native Americans used yew extracts to treat rheumatism, fever, and arthritis.
  • Paclitaxel (Taxol®) was isolated from the bark of the Pacific yew tree (Taxus brevifolia) as early as 1971 and is now approved by the U.S. Food and Drug Administration (FDA). Since 1971, Taxol® has been used as an antitumor drug in clinical trials run by the U.S. National Cancer Institute and has been hailed as one of the most significant advances in cancer chemotherapy in recent history. Since 1990, clinical trials using Taxol® have succeeded in treating advanced ovarian and breast cancers.

Evidence

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Dosing

The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.

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Safety

The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.