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Perilla (Perilla frutescens)

Synonyms/Common Names/Related Substances:

  • l-perillyl alcohol, 7-di-O-beta-glucuronide, alpha-linolenic acid, ao shiso, apigenin, apigenin-4'-O-sulfate-7-O-beta-glucuronide, apigenin-7-O-beta-glucuronide, baisu, ban tulsi (Bengali), beefsteak plant, bhanjira (Hindi), caffeic acid, Chinese basil, chi-ssu (Chinese), common perilla, d-limonene, dihydroperillic acid, diosmetin-7-O-beta-glucuronide, egoma (Japanese), hung-sha-yao (Chinese), ji soo, kkaennip namul (Korean), Labiatae (family), Lamiaceae (family), Lamiaciae herbs, limonene, luteolin, luteolin 7-O-glucuronide-6"-methyl ester, m-hydroxyphenylpropionic acid, methyl caffeate, monoterpene, monoterpene perillyl alcohol, perilla seed oil, perilla seed perillaldehyde, perilla oil, perillic acid, perilloside A, perilloside C, perillyl alcohol, Perilla frutescens, Perilla frutescens Britton var. acuta KUDO (Perillae Herba, Labiatae), Perilla frutescens Britton var. japonica, Perilla frutescens var. crispa f. viridis, purple mint, purple perilla, rattlesnake weed, red perilla, rosmarinic acid, scutellarein-6, trans-caffeic acid, shiso (Japanese), shisonoha (Japanese, red leaved form), summer coleus, trans-caffeic acid-4-O-sulfate, trans-carveol, trans-ferulic acid-4-O-sulfate, trans-m-coumaric acid, trans-m-coumaric acid-3-O-sulfate, trans-p-coumaric acid, trans-p-coumaric acid-4-O-sulfate, ts'ao-t'ou (Chinese), tsu-shih ts'ao (Chinese), tzu ssu (Chinese), wild basil, wild coleus, wild red basil, yeh-ssu (Chinese), zisu.
  • Combination products: Banxia-houpu (a traditional Chinese prescription containing pinellia tuber, magnolia bark, hoelen, perilla herb and ginger rhizome).

Clinical Bottom Line/Effectiveness

Brief Background:

  • Perilla is a traditional crop of China, India, Japan, Korea, Thailand, and other Asian countries.
  • The seed oil is used for cooking, as well as a drying oil, and as a fuel. Perilla seed oil is high in the omega-3 fatty acid, alpha-linolenic acid. Perilla seeds are eaten by people and used as bird seed. The foliage is also distilled to produce an essential oil for flavoring.
  • Asian practitioners prescribe perilla for respiratory afflictions and prevention, pregnancy concerns, seafood poisoning, and 'incorrect energy balance.'
  • Some evidence is available for the use of perilla oil for reduction in asthma symptoms, as well as use of perilla extract for seasonal allergies. More clinical evidence is required before recommendations can be made for any clinical usage of perilla.

Dosing/Toxicology

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Precautions/Contraindications

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Mechanism of Action

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History

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Evidence Table

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Evidence Discussion

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Products Studied

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.