Image for Trumpet satinash ()
Trumpet satinash (Syzygium claviflorum)

Synonyms/Common Names/Related Substances:

  • 1Beta-hydroxy-3-oxo-lup-20(29)-en-28-oic acid, 3beta,7beta,15alpha-trihydroxy-lup-20(29)-en-28-oic acid, 3beta-hydroxy-lup-20(29)-en-28-oic acid, 3-oxo-11alpha-hydroxy-lup-20(29)-en-28-oic acid, 3-oxo-lup-20(29)-en-28-oic acid, Acmenosperma claviflorum, Acmenosperma claviflorum (Roxb.) Kausel, BetA, betulin, betulinic acid, betulinic acid amide, betulinic acid methyl ester, betulinic aldehyde, dehydrocostuslactone, IC9564, lupeol, methyl betulinate, mokko lactone, Myrtaceae (family), NVX-207, oleanolic acid, platanic acid, Syzygium claviflorum, YKFH312.

Clinical Bottom Line/Effectiveness

Brief Background:

  • Trumpet satinash (Syzygium claviflorum) is of the family Myrtaceae, which includes 4,500-5,000 species of evergreen trees or shrubs that are found in the Mediterranean region, sub-Saharan Africa, Madagascar, tropical and temperate Asia, Australia, the Pacific Islands, and tropical and South America. Betulinic acid, a naturally occurring pentacyclic triterpenoid, is the main constituent of trumpet satinash and is believed to be responsible for its effects.
  • Based on in vitro and in vivo evidence, betulinic acid may have antiretroviral (1;2;3;4;5;6;7;8), antimalarial (3;5;6;9), anti-inflammatory (3;5;6;10), and anticancer properties (6;11;12;13;14;15). Based on in vitro and in vivo evidence, betulinic acid may selectively inhibit melanoma by inducing apoptosis (16;17;18;19).
  • There is a lack of clinical evidence in support of the use of trumpet satinash for any indication.

Dosing/Toxicology

  • Content available for subscribers only.

Precautions/Contraindications

  • Content available for subscribers only.

Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

  • Content available for subscribers only.

Mechanism of Action

  • Content available for subscribers only.

History

  • Content available for subscribers only.

Evidence Table

  • Content available for subscribers only.

Evidence Discussion

  • Content available for subscribers only.

Products Studied

  • Content available for subscribers only.

Author Information

  • Content available for subscribers only.

References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

  • Content available for subscribers only.
The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.