Synonyms/Common Names/Related Substances:
- 6,7,8-trihydroxycoumarin, 8-hydroxy-5,6,7-trimethoxycoumarin, African geranium, catechin, coumarin, coumarin sulphates, ellagitannins, EPs 7630®, gallic acid, gallocatechin, Geranien (German), geranium, geranium root, Kalwerbossie (German), Kapland-Pelargonie (German), Kap-Pelargonie (German), O-galloyl-C-glucosylflavones, Pelargonien (German), Pelargonium, Pelargonium reniforme, Pelargonium reniforme Curtis, pelargonium root, Pelargonium sidoides, Pelargonium sidoides DC, Pelargonium sidoides extract, polyphenols, proanthocyanidins, rabassam, Rabassamin (German), scopoletin, South African geramium, tannins, umckalin.
- Note: An ethanolic extract of the roots of Pelargonium sidoides and Pelargonium reniforme has been marketed in Germany under the name "Umckaloabo" since 1983.
Clinical Bottom Line/Effectiveness
Brief Background:
- Pelargonium sidoides, also known as umckaloabo, is a member of the Geranium family and is native to South Africa.
- For centuries the roots of Pelargonium sidoides DC have been used in traditional South African medicine for the treatment of respiratory diseases (1;2), diarrhea, dysmenorrhea, and hepatic disorders (3;4).
- In modern times, an aqueous formulation of the roots of Pelargonium sidoides, called EPs 7630®, has been examined in clinical trials as a potential treatment for bronchitis (acute) (5;6;6;7;8;9), acute pharyngitis (acute non-group A beta-hemolytic streptococcus tonsillopharyngitis) (10), and the common cold (11).
Dosing/Toxicology
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Precautions/Contraindications
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Interactions
Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.
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Mechanism of Action
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History
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Evidence Table
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Evidence Discussion
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Products Studied
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Author Information
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References
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
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