Propolis, a bee product, could reduce the number of outbreaks of recurrent aphthous stomatitis (RAS) ulcers (canker sores).

A new pilot study conducted at the Harvard School of Dental Medicine investigated the potential of the propolis product to reduce the number of outbreaks of RAS ulcers.

Recurrent aphthous stomatitis (RAS) is a common, painful, and ulcerative disorder of the oral cavity of unknown etiology. No cure exists and medications aim to reduce pain associated with ulcers through topical applications or reduce outbreak frequency with systemic medications, many having serious side effects.

In this randomized, double-blind, placebo-controlled study, patients were assigned to take 500 milligrams of propolis or a placebo capsule daily.

Researchers found a statistically significant reduction of outbreaks in the propolis group and patients in the propolis group also self-reported a significant improvement in their quality of life.

From the data, the study authors concluded that propolis may be effective in decreasing the number of recurrences and improve the quality of life in patients who suffer from RAS.

1. Natural Standard Research Collaboration: The Authority on Integrative Medicine. www.naturalstandard.com. Copyright © 2007.
2. Samet N, Laurent C, Susarla SM, et al. The effect of bee propolis on recurrent aphthous stomatitis: a pilot study. Clin Oral Investig. 2007 Feb 7. View Abstract